Reboot with Dr Arasi Maran
Reboot with Dr. Arasi Maran
Back by Popular Demand: Dr. Apurva Modi on Liver Health
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Back by Popular Demand: Dr. Apurva Modi on Liver Health

Summary

Dr. Arasi Maran and Dr. Apurva Modi discuss various aspects of liver disease, including fatty liver and alcoholic liver disease. They highlight the importance of early detection and lifestyle changes in managing liver disease. They also discuss the barriers to eating better and the impact of socioeconomic status on liver health. The conversation concludes with a discussion on the treatment options for alcoholic hepatitis. This conversation covers various topics related to liver health, including liver transplants for alcohol-related liver disease, the impact of chronic alcohol problems, symptoms and diagnosis of liver disease, the effectiveness of liver supplements and detoxing, the benefits of fasting and intermittent fasting, the potential of fecal transplantation, and the role of small intestine bacterial overgrowth (SIBO) in liver health.

Takeaways

- Liver disease is often asymptomatic until complications develop, highlighting the importance of regular liver function tests and ultrasounds for early detection.

- Non-alcoholic fatty liver disease (NAFLD) is a reversible condition that can be managed through lifestyle changes, such as weight loss and adopting a Mediterranean diet.

- A new FDA-approved medication called resmetarone shows promise in treating fatty liver by reducing fat, inflammation, and fibrosis in the liver.

- Socioeconomic factors can contribute to poor dietary habits and make it challenging for individuals to make healthier food choices.

- Alcoholic liver disease includes acute alcoholic hepatitis and alcoholic cirrhosis, with limited treatment options available.

- Liver transplants are typically not offered to individuals with alcoholic liver disease unless they meet strict criteria, including six months of alcohol abstinence. No amount of alcohol is safe for the liver, and combining alcoholic and non-alcoholic fatty liver disease can cause rapid damage.

- Liver disease often has no symptoms until late stages, making early detection challenging.

- Supplements for liver health should be approached with caution, as there is limited evidence for their effectiveness.

- Intermittent fasting can be beneficial for liver health by preventing excess calorie intake and promoting weight loss.

- Small intestinal bacterial overgrowth (SIBO) can cause bloating and discomfort, and can be diagnosed through a hydrogen breath test.

Chapters

00:00 Introduction to Liver Disease

02:35 Early Signs and Diagnosis of Liver Disease

07:11 Progression of Liver Disease: From Fatty Liver to Cirrhosis

09:58 Reversibility of Fatty Liver through Lifestyle Changes

13:47 Barriers to Making Healthier Food Choices

25:10 Acute Alcoholic Hepatitis

30:00 Treatment Options for Alcoholic Liver Disease

30:56 Liver Transplant Criteria

32:20 Chronic Alcohol Problem

33:19 Cirrhosis and Symptoms

34:45 Alcohol Cravings and Treatment

35:44 Waiting Period for Transplant

36:14 Liver Recovery and Prognosis

37:07 Symptoms and Diagnosis of Liver Disease

38:04 Lack of Education on Liver Disease

39:01 Screening for Liver Disease

39:30 Supplements and Liver Health

40:26 Detoxing the Liver

41:17 Fecal Transplantation

41:46 Role of Fecal Transplants in Liver Disease

42:44 Limitations of Eastern Medicine

45:06 Evidence-Based Approach to Supplements

45:45 Intermittent Fasting and Weight Loss

50:31 Mindful Eating and Nutrition

52:22 Fecal Transplantation and Microbiome

54:45 Small Intestinal Bacterial Overgrowth (SIBO)

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